Invasive Alien Species (IAS) and climate change require the development of new capacities to protect the natural capital and manage the rapid transformation of natural resources. The USEit (Using Operational Synergies for the Integrated Management of Invasive Alien Species in Italy) project proposes the development of an integrated and shared approach to improve the management of invasive alien species (IAS) issues, both in marine and terrestrial environments. The goal will be pursued through technical and technological advances supported by studies to improve information management and the use of IAS as a potential economic resource.